Mitochondria: A Key Player in Stem Cell Fate
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چکیده
منابع مشابه
Mitochondria: A Key Player in Stem Cell Fate
Mitochondria are highly dynamic organelles that undergo cycles of fusion and fission important for their function, maintenance, and quality control as well as direct or indirect role in different types of stem cells fate decisions. Stem cells have potential for numerous biomedical applications; however the major bottle neck in stem cell field is the stem cell differentiation and maintenance of ...
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As sites of cellular respiration and energy production, mitochondria play a central role in cell metabolism. Cell differentiation is associated with an increase in mitochondrial content and activity and with a metabolic shift toward increased oxidative phosphorylation activity. The opposite occurs during reprogramming of somatic cells into induced pluripotent stem cells. Studies have provided e...
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Heparan sulfate (HS) belongs to a class of glycosaminoglycans and is a highly sulfated, linear polysaccharide. HS biosynthesis and modification involves numerous enzymes. HS exists as part of glycoproteins named HS proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix. HS interacts with numerous proteins, including growth factors, morphogens, and adhe...
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ژورنال
عنوان ژورنال: Cell Biology
سال: 2015
ISSN: 2330-0175
DOI: 10.11648/j.cb.s.2015030201.15